After the general introduction of the NEUROCLINOMICS project and
discussion of the Alzheimer's Disease case study, we now focus on the
Amyotrophic Lateral Sclerosis problem. The relevant questions we wish to
address are discussed, starting from a diagnosis problem, and then
considering a prognostic prediction. The available datasets are shown,
with their particular characteristics, which many times present a real
challenge by themselves. Finally, we present and discuss the chosen
approaches to deal with the different problems, ending with the outline of
future work.